Peyronie's Disease & Genetics
Are you worried that you may have inherited a bend in your privates or passed it on to your children? Don't get too concerned, we have therapies that can help you overcome the problem.
Find out more how MansMatters can help you
Contact us for a free 20-minute consultation with our men's health specialists.
Arrange a Free Telephone Consultation
Book a Treatment
Receive More Information & Our Explainer Video
![an illustration showing off the sequencing of DNA](/shared/images/content/bus_57146/Peyronies-Disease-Therapy-103.jpg)
Evaluating the Role of Genetics in Peyronie's Disease
Over the past 40 years, a number of studies have been undertaken but none have definitively shown genetics as a cause for Peyronie's disease.
However, there are a number of factors that support the theory that genetics play a part. Peyronie's disease has a far higher occurrence in Caucasian men than in other ethnic groups. Like other diseases found in specific ethnicities for example Cystic Fibrosis, the higher prevalence suggests the presence of a founder mutation.
Peyronie's disease and Dupuytren's contracture
Peyronie's disease is known a fibroproliferative disease. With Peyronie's disease a fibrous plaque develops in the fibrous envelope that stretches the length of your manhood. There is a strong correlation with other fibroproliferative diseases such as Dupuytren's contracture, which is a deformity of the hand, where knots of tissue form under the skin, which develop into thick cords that pull one or more fingers into a bent position.
Over 20% of men with Dupuytren's contracture also have been found to have Peyronie's disease, and Dupuytren's contracture is often found in families with a high prevalence of Peyronie's disease. This overlap of symptoms suggests a common genetic predisposition.
Many men can remember a traumatic event, such as being injured during intercourseor being hit by a cricket ball that triggered off their Peyronie's disease. However, very few men go through life, without at some stage being injured and experiencing severe pain in their private parts - But only a few develop Peyronie's disease.
This suggest that some individuals are ready primed to develop the disease in response to a trauma, whereas others can experience a major trauma and not develop the condition. This too suggests there is a greater link to genetics.
Knightsbridge
Richmond
MansMatters are specialists in non-invasive, nonsurgical procedures. We do not offer surgery but have professional relationships with leading surgical urologists and andrologists who undertake different types of Peyronie's disease surgery. If you would like to know more about surgical options, then please click here.
Surgical Procedures